Supermicro SYS-521E-WR 2U UP Server
2U UP WIO with 8 hot-swap 3.5″ SAS/SATA (4 NVMe hybrid) bays and up to 5 PCIe 5.0 slots
Description
Product overview
2U UP WIO with 8 hot-swap 3.5" SAS/SATA (4 NVMe hybrid) bays and up to 5 PCIe 5.0 slots
Key capabilities
- Form Factor: 2U Rackmount Enclosure: 437 x 89 x 647mm (17.2" x 3.5" x 25.5") Package: 673.1 x 279.4 x 863.6mm (26.5" x 11" x 34")
- Processor: Single Socket E (LGA-4677) 5th Gen Intel® Xeon®4th Gen Intel® Xeon® Scalable processors Up to 52C/104T; Up to 300MB Cache GPU Max GPU Count: Up to 1 double-width or 2 single-width GPUs Supported GPU: NVIDIA PCIe: RTX 4500 Ada, RTX 5000 Ada, RTX A2000, RTX A4000, RTX A4500, RTX A5000, RTX A6000, T400 CPU-GPU Interconnect: PCIe 5.0 x16 CPU-to-GPU Interconnect
- System Memory: Slot Count: 8 DIMM slots/8 Channels Max Memory (1DPC): Up to 2TB 5600MT/s ECC DDR5 RDIMM
- Drive Bays Configuration: Default: Total 8 bays 8 front hot-swap 3.5" SAS*/SATA drive bays Option A: Total 8 bays 4 front hot-swap 3.5" PCIe 5.0 x4 NVMe* drive bays 4 front hot-swap 3.5" SAS*/SATA drive bays (*NVMe/SAS support may require additional storage controller and/or cables, please see the optional parts list for details) M.2: 1 M.2 PCIe 3.0 x2 NVMe slot (M-key 2280/22110) Peripheral Bays: 2 2.5" bays (optional)
- Expansion Slots: Default 2 PCIe 5.0 x16 FHFL double-width slots 2 PCIe 5.0 x8 LP slots Option A* 1 PCIe 5.0 x16 FHFL double-width slot 2 PCIe 5.0 x8 FHFL slots 2 PCIe 5.0 x8 LP slots
Technical specifications
| Form Factor | 2U Rackmount Enclosure: 437 x 89 x 647mm (17.2" x 3.5" x 25.5") Package: 673.1 x 279.4 x 863.6mm (26.5" x 11" x 34") |
|---|---|
| Processor | Single Socket E (LGA-4677) 5th Gen Intel® Xeon®4th Gen Intel® Xeon® Scalable processors Up to 52C/104T; Up to 300MB Cache GPU Max GPU Count: Up to 1 double-width or 2 single-width GPUs Supported GPU: NVIDIA PCIe: RTX 4500 Ada, RTX 5000 Ada, RTX A2000, RTX A4000, RTX A4500, RTX A5000, RTX A6000, T400 CPU-GPU Interconnect: PCIe 5.0 x16 CPU-to-GPU Interconnect |
| System Memory | Slot Count: 8 DIMM slots/8 Channels Max Memory (1DPC): Up to 2TB 5600MT/s ECC DDR5 RDIMM |
| Drive Bays Configuration | Default: Total 8 bays 8 front hot-swap 3.5" SAS*/SATA drive bays Option A: Total 8 bays 4 front hot-swap 3.5" PCIe 5.0 x4 NVMe* drive bays 4 front hot-swap 3.5" SAS*/SATA drive bays (*NVMe/SAS support may require additional storage controller and/or cables, please see the optional parts list for details) M.2: 1 M.2 PCIe 3.0 x2 NVMe slot (M-key 2280/22110) Peripheral Bays: 2 2.5" bays (optional) |
| Expansion Slots | Default 2 PCIe 5.0 x16 FHFL double-width slots 2 PCIe 5.0 x8 LP slots Option A* 1 PCIe 5.0 x16 FHFL double-width slot 2 PCIe 5.0 x8 FHFL slots 2 PCIe 5.0 x8 LP slots |
| On-Board Devices | SATA: SATA (6Gbps); RAID 0/1/5/10 support NVMe: NVMe; RAID 0/1/5/10 support(Intel® VROC RAID key required) Network Connectivity: 2 RJ45 1GbE with Intel® I210 DATASHEET More details here |
| Input / Output | LAN: 2 RJ45 1 GbE LAN ports 1 RJ45 1 GbE Dedicated BMC LAN port (IPMI shared on LAN port 1) USB: 2 USB 3.2 Gen1 Type-A ports (rear) 2 USB 2.0 Type-A ports (rear) 2 USB 3.2 Gen1 ports (Header) 1 USB 2.0 Type-A port (Header) Video: 1 VGA port Serial: 1 COM port (header) 1 COM port (rear) TPM: 1 TPM header ©2026 Copyright Super Micro Computer, Inc. All rights reserved. |
| System Cooling | Fans: Up to 3 heavy duty PWM 80x80x38mm Fan(s) Air Shroud: 1 Air Shroud |
| Power Supply | 2x 1000W Redundant (1 + 1) Titanium Level (96%) power supplies |
| System BIOS | BIOS Type: AMI 32MB SPI Flash EEPROM |
| Management | SuperCloud Composer® (SCC); Supermicro Server Manager (SSM); Supermicro Update Manager (SUM); Supermicro SuperDoctor® 5 (SD5); Super Diagnostics Offline (SDO); Supermicro Thin-Agent Service (TAS); SuperServer Automation Assistant (SAA) New! PC Health Monitoring CPU: 8 Phase-switching voltage regulator Monitors for CPU Cores, Chipset Voltages, Memory Fan: Fans with tachometer monitoring Pulse Width Modulated (PWM) fan connectors Status monitor for speed control Temperature: Monitoring for CPU and chassis environment Thermal Control for fan connectors |
| Dimensions and Weight | Weight: Gross Weight: 59 lbs (26.76 kg) Net Weight: 34 lbs (15.42 kg) Available Color: Black |
| Operating Environment | Operating Temperature: 10°C to 35°C (50°F to 95°F) Non-operating Temperature: -30°C to 60°C (-22°F to 140°F) Operating Relative Humidity: 8% to 80% (non-condensing) Non-operating Relative Humidity: 8% to 90% (non-condensing) |
| Motherboard | Super X13SEW-F |
| Chassis | CSE-825B2TS-R0WNP |
Configuration note
Processor, memory, storage, networking, accelerator, power, cooling and regional order codes may vary by configuration. GPULoom confirms the exact bill of materials and compatibility for each inquiry.




